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.: CORNEAL EDEMA – CAUSES AND TREATMENT

Corneal edema is a frequent pathologic condition, particularly common among people above 50, in which the cornea presents an abnormal build-up of fluids, with or without inflammation.

In order to remain transparent, the cornea is normally kept perfectly hydrated by the draining action of the corneal endothelium. Any change in the dehydration process and other pathologic conditions may disturb this mechanism and lead to the accumulation of fluids, consequently preventing light beams from moving through the cornea and therefore resulting in impaired vision.

Symptoms of corneal edema include blurred vision, halos around lights etc. As the early symptoms of corneal edema are similar to those of cataract, eye examination is required for proper diagnosis. Corneal edema may turn into a chronic condition. When the situation deteriorates, corneal nervous fibers suffer alterations and become exposed, resulting in intense pain (late symptoms). The treatment of an acute edema may include corneal transplantation...

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Bibliography

1. LEVENSON, J. E., et al , Survey of Ophthalmology, 20:3 (1975) 190.

2. PRICE, F. W. JR.,et al, Ophthalmology, 98 (1991) 322.

3. OHGURO, N.,et al. Am. J.Ophthalmol., 112 (1991) 424.

4. OBATA, H., et al , Jpn. J. Ophthalmol., 35 (1991) 411.

5. KANSKI, J. J.: Clinical Ophthalmology. (Butterrworth-Heinmann, Oxford, 1999).

6. BROOKS A. M., et al Aust. N. Z. J. Ophthalmol., 16 (1988) 93.

7. BRAMSEN,T., N. EHLERS, Acta Ophthalmol. (Copenh)., 55 (1977) 665.

8. TAKA-HASHI G. H., et al , Arch. Ophthalmol., 86 (1971) 133.

9. MARISI, A., et al , Ann. Ophthalmol., 7 (1975) 229.

10. MANSOUR, A. M., et al, Acta Ophthalmol.Scand., 82 (2004) 312.

11. HODVING, G. Acta Ophthalmol. (Copenh).,62 (1984) 566.

12. SIENNICKA, A., et al, Klin. Oczna., 105 (2003) 41.

13. GABRI], N., et al., Doc. Ophthalmology, 98 (1999) 273.

14. WHITSON, J. T., et al, Eye Contact Lens, 31 (2005) 221.

15. KNEZOVIC I. et al Coll. Antropol.30 (2006) 405-408

16. BERGMANSON et al. Fuchs’ endothelial dystrophy: a fresh look at an aging disease. Ophthal. Physiol. Opt. 19, 3. 210-222, 1999

 
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lutein omega 3
Composition
 
Sodium chloride 5%
Disodium EDTA 0.1%
N-hydroxymethylglycinate 0.004
 
 
Description

EDENORM® 5%, a hypertonic ophthalmic solution specific for the treatment of corneal edema.

Corneal edema is a common pathologic condition, in particular in people above 50 years of age. Corneal edema means the cornea presents an abnormal build-up of fluids, with or without inflammation. It may be secondary to eye surgery (refractive, vitreoretinal, cataract removal, corneal transplantation), keratitis (of chemical, physical – such as trauma – or biological nature, such as in case of infections), alterations of osmotic balance during eye examination, use of contact lenses (corneal warpage), bullous keratopathy and Fuchs' dystrophy.

Corneal edema is certainly very uncomfortable for the patient, as symptoms include distorted and hazed vision, halos around lights and, as late symptoms, intense pain due to the alteration and exposure of corneal nervous fibers. Quickly solving a corneal edema therefore provides the patient with a sense of well-being, and results in professional satisfaction for any physician.

 
 
Indications

USE
Edenorm®, a hypertonic ophthalmic solution specific for the treatment of corneal edema.
By making tears hypertonic, Edenorm uses the osmotic effect to draw excess fluid from the corneal tissue, therefore reducing the edema.

The purposes of the therapy with Edenorm® are: increasing vision quality by reducing the irregularities on the surface; reducing the discomfort caused to the rupture of bubbles, which exposes the nervous ends; preventing complications secondary to edema, such as ulcerations and infections.
The quick reduction of the corneal edema may therefore offer relief for the eye discomfort and the irritation consequent to the edema itself.

DOSAGE AND ADMINISTRATION
Instill 1-2 drops on the conjunctival sac 4 times a day or as prescribed by your physician. After instillation keep the eye closed for 1 or 2 minutes, without squinting.

PACKAGING
8 ml-phial

 
 
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