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AMINO ACIDS FOR THE OCULAR SURFACE

Amino acids, as is known, play an important role In many pathologies of the nervous system, as well as In skin diseases, favoring cellular trophism, perhaps even more so than the well renown vitamins. Tests have highlighted the specific role played by amino acids in proliferation and functional activities of human skin fibroblasts. Amino acids have the supposed ability to directly stimulate the production of collagen by the fibroblasts to favor the healing of ulcers of various ethiopathogenisi (arterial, venal, diabetic, decubitus ulcer). Their potency could be greater diffused, given that it Is widely known that fibroblasts play an important role in releasing growth factors and in communicating with surrounding cells…

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Different concentrations of amino acids in tears and integrity of the ocular surface. by Giulio Luciani, MD
by Giulio Luciani, MD

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nextal
Composition
 
Hypermellose 0,500 g
N-hydroxymethylglycinate 0,002 g
Sodium edetate 0,100 g
L-proline 0,0752 g
L-Glicine 0,100 g
L- chlorhydrate lysine 0,014 g
L-leucine 0,0108 g
Buffed isotonic solution at pH 7,2 q.b. at ml 100
 
Description

NEXTAL® gel is a sterile ophthalmic solution based on hypermellose and amino acids N-IG

Hypermellose is a polymer that has the property of thickening and stabilizing the tear film on the ocular surface thus creating a protective shield that is both transparent and viscoelastic.

The amino acids L-proline, L-glycine, L-chlorhydrate lysine and L-leucine, contained in the product increase lubrication of the ocular surface and can lend a hand in protecting the epitelium subject to stress of varying nature.

Sodium hydroxymethylglycinate (N-IG), contained in Nextal®gel is a new amino acid derivate that exerts an efficient action of conservation thanks to its antimicrobial action; and causes no harmful effects on the ocular surface.

NEXTAL® gel is a hydrating and lubricating tear substitute for the treatment of ocular ailments caused by tear deficiency (dry eye syndrome), environmental, visual or mechanical stress. It is especially indicated in severe cases of dry eye syndrome and nighttime protection of the ocular surface.

NEXTAL® gel, evenly spreads on the ocular surface and perfectly adheres to it, in order to provide protection, moisture and lubrication. Offers lasting relief against dry eye syndrome (burning, dryness or foreign bodies, etc.).

NEXTAL® gel, thanks to its mucoadhesive, mucomimetic and humectant properties, Is particularly helpful In cases of severe dry eye syndrome when in need of greater lubrication and protection both during the day and night. Nextal®gel also efficiently combats ocular symptoms caused by irritating environmental agents (pollution), visual causes (intense use of eyesight) and mechanical causes (contact lenses).

 
Product Use

MODE OF USE
Instill 1-2 drops in the conjunctival sac 2-3 times a day or more as necessary. For nighttime protection, instill a drop when going to sleep. The product can be instilled into the eye even when wearing contact lenses.

PACKAGE
Contains one multidose container (8ml)

 
 
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